Nandrolone Decanoate
Long-acting 19-nortestosterone derivative with extensive pharmacological documentation.
Nandrolone Decanoate
Nandrolone Decanoate is a sterile oil-based injectable preparation of nandrolone esterified with decanoic acid, presented at 250 milligrams per millilitre in a 10 mL multiple dose vial. Nandrolone is among the most extensively documented anabolic compounds in the medical literature, with a clinical record extending over five decades.
Structural Profile
Nandrolone is 19-nortestosterone: testosterone lacking the methyl group at carbon 19. This single structural difference substantially raises the anabolic-to-androgenic ratio relative to the parent hormone. The decanoate ester at the 17-beta position gives the molecular formula C28H44O3 and a molar mass of 428.65 g/mol, registered under CAS number 360-70-3.
Esterification and Release
The ten-carbon decanoate chain is among the longest esters in pharmaceutical use and produces a markedly prolonged depot. Partition from the oil vehicle into plasma proceeds slowly and steadily, so that a single administration maintains measurable serum concentrations for two to three weeks.
Pharmacokinetic Profile
The elimination half-life is approximately 6 to 7 days. Serum concentrations rise over the first days following administration and decline gradually thereafter. The urinary detection window is exceptionally long, extending to approximately 18 months, because nandrolone metabolites such as 19-norandrosterone are retained in adipose tissue and released slowly.
Mechanism of Action
Nandrolone binds the cytoplasmic androgen receptor with high affinity; the hormone-receptor complex translocates to the nucleus and engages androgen response elements, increasing transcription of genes governing structural protein synthesis and nitrogen retention. Unlike testosterone, nandrolone is reduced by 5-alpha reductase to dihydronandrolone, a metabolite of markedly lower androgenic potency, which accounts for the favourable anabolic-to-androgenic profile. Aromatisation to oestrogenic metabolites occurs at roughly one fifth the rate observed with testosterone.
Manufacturing and Sterility
Each production lot is released against the complete pharmaceutical testing protocol: HPLC identity confirmation and purity analysis with a specification of not less than 98 percent, verification of concentration against label claim within 5 percent, sterility testing in accordance with USP <71>, bacterial endotoxin quantification by LAL assay below 0.25 EU/mL, and particulate matter inspection in accordance with USP <788>. A Certificate of Analysis is issued for every lot.
Quality Assurance
Every batch of Nandrolone Decanoate produced by Biomedica undergoes the complete pharmaceutical release testing protocol before distribution. This includes HPLC compound identity confirmation and purity analysis (specification: ≥98%), concentration verification (specification: ±5% of label claim), sterility testing per USP <71>, bacterial endotoxin quantification by LAL assay (specification: <0.25 EU/mL), and particulate matter inspection per USP <788>. A Certificate of Analysis is issued for every production lot.
Authentication
Each unit of Nandrolone Decanoate carries a unique authentication code on its outer packaging. This code can be verified instantly on our Authentication page to confirm the product is genuine Biomedica stock.