Testosterone Cypionate
Extended-release testosterone compound with 8-day half-life for minimal fluctuation.
Testosterone Cypionate
Testosterone Cypionate is a sterile oil-based injectable preparation of testosterone esterified with cyclopentylpropionic acid, presented at 250 milligrams per millilitre in a 10 mL multiple dose vial. Its cyclic ester structure produces the longest release profile among the commonly used single testosterone esters.
Structural Profile
The compound is the 17-beta cyclopentylpropionate ester of testosterone, with the molecular formula C27H44O3 and a molar mass of 412.61 g/mol, registered under CAS number 58-20-8. The cyclopentyl ring distinguishes it structurally from the straight-chain enanthate ester and accounts for its marginally slower hydrolysis and longer duration of action.
Esterification and Release
The eight-carbon cyclic ester is more lipophilic than enanthate, which prolongs residence in the intramuscular depot. Release into systemic circulation is correspondingly gradual and the resulting serum curve is exceptionally stable, with minimal peak-to-trough fluctuation between administrations.
Pharmacokinetic Profile
The elimination half-life is approximately 8 days, the longest of the standard testosterone esters. Peak serum concentrations are reached within 24 to 48 hours and decline slowly thereafter. The urinary detection window for metabolites extends to approximately 3 months, again a reflection of extended depot release.
Mechanism of Action
After hydrolysis of the ester bond, testosterone binds the cytoplasmic androgen receptor. The activated complex translocates to the nucleus and interacts with androgen response elements, increasing transcription of genes responsible for structural protein synthesis and nitrogen retention in skeletal muscle. Peripheral conversion by aromatase to oestradiol and by 5-alpha reductase to dihydrotestosterone completes the physiological profile.
Manufacturing and Sterility
Each production lot is released against the complete pharmaceutical testing protocol: HPLC identity confirmation and purity analysis with a specification of not less than 98 percent, verification of concentration against label claim within 5 percent, sterility testing in accordance with USP <71>, bacterial endotoxin quantification by LAL assay below 0.25 EU/mL, and particulate matter inspection in accordance with USP <788>. A Certificate of Analysis is issued for every lot.
Quality Assurance
Every batch of Testosterone Cypionate produced by Biomedica undergoes the complete pharmaceutical release testing protocol before distribution. This includes HPLC compound identity confirmation and purity analysis (specification: ≥98%), concentration verification (specification: ±5% of label claim), sterility testing per USP <71>, bacterial endotoxin quantification by LAL assay (specification: <0.25 EU/mL), and particulate matter inspection per USP <788>. A Certificate of Analysis is issued for every production lot.
Authentication
Each unit of Testosterone Cypionate carries a unique authentication code on its outer packaging. This code can be verified instantly on our Authentication page to confirm the product is genuine Biomedica stock.